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While Jeff was looking under the microscope at cells in different stages of mitosis, he commented on the fact that many cells were in the same stage. If you were looking under the compound light microscope at an onion root tip, in what stage of the cell cycle would the majority of the cells be?


A) anaphase
B) metaphase
C) cytokinesis
D) interphase
E) prophase

F) C) and D)
G) B) and E)

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The figure below shows a cell in which stage of the cell cycle? The figure below shows a cell in which stage of the cell cycle?   A)  anaphase B)  interphase C)  metaphase D)  prophase E)  telophase


A) anaphase
B) interphase
C) metaphase
D) prophase
E) telophase

F) B) and D)
G) B) and C)

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The G2 checkpoint prevents the cell cycle from continuing until


A) DNA is completely replicated.
B) damage to DNA can be repaired.
C) replicated DNA is separated.
D) organelles have been duplicated.
E) DNA is completely replicated and damage to DNA can be repaired.

F) None of the above
G) A) and E)

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Some multicellular organisms, like the hydra, use asexual reproduction to produce a bud that leads to a new organism. This means that they are using


A) binary fission to create new cells.
B) mitotic division to create new cells that become a new organism.
C) meiosis to create new cells that become a new organism.
D) mitotic division to create gametes that give rise to a new organism.
E) meiosis I only to give rise to new organisms.

F) All of the above
G) None of the above

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Which is not a correct association?


A) interphase - shortest stage of the cell cycle
B) S stage - DNA synthesis
C) M stage - mitosis and cytokinesis
D) G1 stage - cell grows in size and cell organelles increase in number
E) G2 stage - metabolic preparation for mitosis

F) All of the above
G) A) and E)

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All of the following occur during the latter stages of mitotic prophase except the


A) coiling of chromosomes.
B) division of centromeres.
C) formation of spindles.
D) synthesis of DNA.
E) degradation of the nuclear envelope.

F) B) and E)
G) A) and D)

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Cytokinesis in plants occurs as ________ and in animals as ________.


A) actin fibers pull the membrane inward until the two sides touch; the Golgi apparatus produces membrane-bound vesicles filled with materials to make the cell wall
B) the Golgi apparatus produces membrane-bound vesicles filled with materials to make the cell wall; actin fibers pull the membrane inward until the two sides touch
C) the centrosome produces membrane-bound vesicles filled with materials to make the cell wall; the Golgi apparatus produces actin fibers to pull the membrane inward until the two sides touch
D) actin fibers interact to make the cell wall; the cleavage furrow pulls the membrane inward until the two sides touch
E) the Golgi apparatus produces a cleavage furrow; actin fibers pull the membrane inward until the two sides touch

F) A) and E)
G) A) and D)

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B

Unicellular organisms undergo mitotic division to


A) repair damaged cells.
B) increase the size of the organism.
C) produce new organisms.
D) increase the genetic variability of the population.
E) produce gametes.

F) A) and C)
G) A) and B)

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Which of the following is not a characteristic of cancer cells?


A) stimulate the growth of blood vessels
B) travel through the bloodstream to other parts of the body
C) exhibit contact inhibition
D) have abnormal chromosomes
E) produced by a mutation of a proto-oncogene

F) B) and C)
G) A) and E)

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Susan was examining a cell under the microscope and noticed the formation of a cell plate in the midline of the cell and the formation of nuclei at opposite poles of the cell. The cell under examination was most likely an)


A) animal cell in the M phase of the cell cycle.
B) dividing bacterial cell.
C) plant cell undergoing cytokinesis.
D) animal cell undergoing cytokinesis.
E) plant cell in the anaphase stage.

F) A) and B)
G) A) and C)

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Cancer is a disorder in which some cells have lost the ability to control their


A) size.
B) spindle fibers.
C) rate of cell division.
D) surface area.
E) volume.

F) C) and D)
G) B) and C)

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Cancer occurs when


A) cells are unable to divide because of a mutation.
B) faulty spindle fibers are unable to pull chromatids apart.
C) apoptosis occurs.
D) both uncontrolled cell division and stimulation of apoptosis occurs.
E) the regulation of the cell cycle is lost and uncontrolled cell division occurs.

F) A) and C)
G) B) and D)

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If tumor cells have a faulty, nonfunctional proteinase, they will be unable to undergo which of the following processes?


A) mitosis
B) mutations
C) metastasis
D) apoptosis
E) angiogenesis

F) All of the above
G) None of the above

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C

During which stage of the cell cycle do the chromosomes duplicate?


A) interphase: S
B) interphase: G1
C) interphase: G2
D) prophase
E) telophase

F) A) and D)
G) A) and E)

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Which cancer therapy can lead to side effects such as nausea and hair loss?


A) chemotherapy
B) surgery
C) hormonal therapy
D) drug therapy
E) All of these can lead to nausea and hair loss.

F) None of the above
G) B) and D)

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Refer to the figure below. Differentiated cells, such as nerve cells, would be in which of the following stages of the cell cycle? Refer to the figure below. Differentiated cells, such as nerve cells, would be in which of the following stages of the cell cycle?   A)  a B)  b C)  c D)  d E)  e


A) a
B) b
C) c
D) d
E) e

F) A) and B)
G) C) and D)

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A translocation may lead to cancer if it


A) disrupts control of expression of genes that regulate the cell cycle.
B) deletes the telomere of the chromosome.
C) moves genes from one chromosome to another.
D) activates tumor suppressor genes.
E) affects both tumor suppressor and proto-oncogenes.

F) B) and C)
G) C) and D)

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A woman inherits a mutant BRCA1 allele from her mother. She has an increased risk of developing breast cancer because


A) every cell in the woman's body has a copy of the mutant BRCA1 allele.
B) she still has one normal allele of the BRCA1 gene that can make up for the loss of function in the mutant allele.
C) some of the cells in her body are already cancerous, meaning that no further mutations are needed for a tumor to form.
D) the normal BRCA1 allele is more likely to mutate than in an individual without a mutant BRCA1 allele.
E) a mutation in her normal BRCA1 allele may lead to cancer, whereas a normal individual would have to acquire two mutations one in each allele) to develop cancer.

F) A) and D)
G) A) and E)

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E

An oncogene is more likely to lead to cancer than a mutant tumor suppressor gene because


A) a gain of function mutation in an oncogene need only occur in one allele before it disrupts control of the cell cycle.
B) a loss of function mutation in an oncogene is sufficient to cause unregulated cell division.
C) the mutant oncogene may inactivate telomerase.
D) a gain of function mutation in a tumor suppressor gene can promote the cell cycle.
E) a gain of function mutation in an oncogene is more likely to cause the other allele to mutate.

F) A) and B)
G) A) and D)

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The term metastasis refers to the fact that cancer cells tend to


A) destroy.
B) divide.
C) decline.
D) shrink.
E) spread.

F) A) and B)
G) B) and D)

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