Question 1

Which of the following statements about eukaryotic genomes is false?

Accepted Answer

A)   They tend to be larger than prokaryotic genomes.
B)   They tend to have more regulatory sequences than prokaryotic genomes.
C)   The percentage of the genome devoted to coding sequence is higher than in prokaryotic genomes.
D)   They usually have more repetitive DNA than prokaryotic genomes.
E)   All of the above are true; none is false.F) A) and D)
G) A) and C)

Question 2

Which of the following is an example of a secondary metabolite?

Accepted Answer

A)   Tannins produced by oak trees to ward against herbivores
B)   The enzyme phosophofructokinase used in glycolysis
C)   Hemoglobin used to carry oxygen in the blood
D)   Both a and b
E)   Both b and cF) A) and B)
G) A) and C)

Question 3

A promoter is an example of a(n)

Accepted Answer

A)   open reading frame.
B)   transposable element.
C)   chromatin sequence.
D)   rRNA gene.
E)   regulatory sequence.F) B) and C)
G) A) and B)

Question 4

By necessity, which of the following will be included in an open reading frame?

Accepted Answer

A)   A transposable element
B)   A start codon
C)   A chromatin sequence
D)   Regulatory sequences
E)   All of the aboveF) None of the above
G) A) and B)

Question 5

Studies using selective gene inactivation have allowed researchers to estimate the _______ genome size of bacteria.

Accepted Answer

The answer of Studies using selective gene inactivation have allowed...

Question 6

Comparative genomics has shown that

Accepted Answer

A)   chimpanzees and humans shared a common ancestor.
B)   humans descended from chimpanzees.
C)   genes for enzymes of metabolism are similar in prokaryotes and eukaryotes.
D)   many genes are unique to plants.
E)   a, c, and dF) C) and E)
G) A) and D)

Question 7

The sequencing of the human genome has allowed scientists to

Accepted Answer

A)   understand regulatory sequences that are important for gene expression.
B)   locate genes that cause disease.
C)   understand evolutionary relationships by comparing human genes to genes in other organisms.
D)   investigate gene families and their origins.
E)   All of the aboveF) A) and D)
G) A) and E)

Question 8

Which of the following statements about chromosome structure and function is false?

Accepted Answer

A)   Telomere sequences are found at the ends of chromosomes.
B)   Remodeling of chromatin structure can alter gene expression.
C)   A chromosome has a single DNA molecule.
D)   Short tandem repeats are an example of noncoding DNA.
E)   All of the above are true; none is false.F) B) and D)
G) B) and C)

Question 9

Which of the following is a disadvantage of shotgun sequencing as compared to hierarchical sequencing?

Accepted Answer

A)   Shotgun sequencing requires a more detailed genetic map.
B)   Shotgun sequencing requires the use of bacterial artificial chromosomes.
C)   Shotgun sequencing is more expensive.
D)   Shotgun sequencing relies more on careful aligning of DNA fragments.
E)   None of the aboveF) A) and E)
G) B) and C)

Question 10

Why do different organisms show more similarities in their proteomes than in their genomes?

Accepted Answer

More sequence similarities are revealed ...

Question 11

Which of the following is likely to be found in a eukaryotic genome but not in a prokaryotic one?

Accepted Answer

A)   Regulatory sequences
B)   Coding sequences
C)   Open reading frames
D)   RNA genes
E)   Telomeric sequencesF) D) and E)
G) A) and E)

Question 12

Metabolomics

Accepted Answer

A)   is the quantitative description of all of the small molecules in an organism.
B)   includes primary metabolites.
C)   includes secondary metabolites.
D)   requires sophisticated methods for separating small molecules.
E)   All of the aboveF) C) and E)
G) A) and C)

Question 13

The DNA sequences that code for eukaryotic rRNA

Accepted Answer

A)   are transcribed only at the ribosome.
B)   are repeated hundreds of times.
C)   contain all the genes clustered directly beside one another.
D)   are on only one human chromosome.
E)   are identical to the sequences that code for miRNA.F) C) and D)
G) B) and C)

Question 14

Which of the following statements about the globin genes in humans is false?

Accepted Answer

A)   They are all expressed at the same time.
B)   They all arose from a single common ancestor gene a long time ago.
C)   They are an example of a gene family.
D)   Some of the different genes carry out different functions.
E)   All of the above are true; none is false.F) B) and E)
G) All of the above

Question 15

Which of the following would not be required for the purpose of determining the sequence of a 400-base-pair DNA fragment by the standard ddNTP sequencing method?

Accepted Answer

A)   The four dNTPs (dATP, dCTP, dGTP, dTTP) 
B)   DNA polymerase
C)   A short, artificially synthesized primer
D)   A bacterial artificial chromosome
E)   All of the above would be required.F) A) and D)
G) B) and D)

Question 16

Shotgun DNA sequencing differs from hierarchical DNA sequencing in that

Accepted Answer

A)   fragments with overlapping sequences are not needed for shotgun sequencing.
B)   specific markers are required for hierarchical DNA sequencing.
C)   shotgun DNA sequencing does not require amplification of the DNA.
D)   multiple cutting of the DNA is not needed for shotgun DNA sequencing.
E)   genomic libraries are used only in shotgun sequencing.F) A) and B)
G) B) and C)

Question 17

A 10 base-pair single-stranded DNA fragment was cut by three different restriction enzymes to produce the following fragments: 
(1)  AC, TAC, and GGATG
(2) TA, CGG, and ATGAC
(3)  GAC, GAT, and TACG.
The nucleotide sequence of the ten base fragment is

Accepted Answer

A)   ATGCCTACTG.
B)   TACGGATGAC.
C)   GGATGACTAC.
D)   GACGATTACG.
E)   The sequence cannot be determined from the information given.F) A) and E)
G) B) and E)

Question 18

Closely linked SNPs that differ among individuals usually are inherited as a unit known as a(n) _______.

Accepted Answer

The answer of Closely linked SNPs that differ among individuals...

Question 19

Comparison of the genomes of prokaryotes has revealed several differences. Which of the following characteristics of genomes is quite similar in prokaryotes and eukaryotes?

Accepted Answer

A)   The presence of introns
B)   Genome size
C)   Percentage of the genome that codes for proteins
D)   Genes that code for the enzymes in the glycolytic pathway
E)   Number of genesF) A) and D)
G) B) and E)

Question 20

The Human Genome Project could not have proceeded without the new field of _______, which uses complex mathematics and computer programs to analyze DNA sequences.

Accepted Answer

The answer of The Human Genome Project could not have...

Exam 17: Genomes

Which of the following statements about eukaryotic genomes is false?

Correct AnswerverifiedShow Answer

Comparison of the genomes of prokaryotes has revealed several differences. Which of the following characteristics of genomes is quite similar in prokaryotes and eukaryotes?

Correct AnswerverifiedShow Answer

The Human Genome Project could not have proceeded without the new field of _______, which uses complex mathematics and computer programs to analyze DNA sequences.

Correct AnswerverifiedShow Answer

By necessity, which of the following will be included in an open reading frame?

Correct AnswerverifiedShow Answer

Why do different organisms show more similarities in their proteomes than in their genomes?

Correct AnswerverifiedMore sequence similarities are revealed ...View AnswerShow Answer

Closely linked SNPs that differ among individuals usually are inherited as a unit known as a(n) _______.

Correct AnswerverifiedShow Answer

The sequencing of the human genome has allowed scientists to

Correct AnswerverifiedShow Answer

Shotgun DNA sequencing differs from hierarchical DNA sequencing in that

Correct AnswerverifiedShow Answer

A promoter is an example of a(n)

Correct AnswerverifiedShow Answer

Studies using selective gene inactivation have allowed researchers to estimate the _______ genome size of bacteria.

Correct AnswerverifiedShow Answer

Which of the following is an example of a secondary metabolite?

Correct AnswerverifiedShow Answer

Which of the following is likely to be found in a eukaryotic genome but not in a prokaryotic one?

Correct AnswerverifiedShow Answer

Which of the following statements about chromosome structure and function is false?

Correct AnswerverifiedShow Answer

Which of the following would not be required for the purpose of determining the sequence of a 400-base-pair DNA fragment by the standard ddNTP sequencing method?

Correct AnswerverifiedShow Answer

Comparative genomics has shown that

Correct AnswerverifiedShow Answer

Metabolomics

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Which of the following statements about the globin genes in humans is false?

Correct AnswerverifiedShow Answer

Which of the following is a disadvantage of shotgun sequencing as compared to hierarchical sequencing?

Correct AnswerverifiedShow Answer

A 10 base-pair single-stranded DNA fragment was cut by three different restriction enzymes to produce the following fragments: (1) AC, TAC, and GGATG (2) TA, CGG, and ATGAC (3) GAC, GAT, and TACG. The nucleotide sequence of the ten base fragment is

Correct AnswerverifiedShow Answer

The DNA sequences that code for eukaryotic rRNA

Correct AnswerverifiedShow Answer

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More sequence similarities are revealed ...
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