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Consensus sequences involved in splicing are located


A) at the centers of introns.
B) at the centers of exons.
C) on introns bordering each splice site.
D) at 5 caps.
E) at poly A tails.

F) A) and E)
G) None of the above

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Refer to the figure, which shows the genetic code. Refer to the figure, which shows the genetic code.   Which amino acid does CGG code for? Which amino acid does CGG code for?

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The gene for the reverse transcriptase enzyme, which is used to reverse transcribe viral RNA into DNA in infected cells, is found in the


A) host cell genome.
B) bacterial plasmid genome.
C) mitochondrial genome.
D) genome of retroviruses.
E) genome of DNA viruses.

F) C) and E)
G) B) and D)

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Which type of molecule transfers information from the nucleus to the cytoplasm in the eukaryotic cell?


A) DNA
B) mRNA
C) tRNA
D) Protein
E) Lipid

F) All of the above
G) B) and E)

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Given that a 5-to-3 strand of DNA is ATGTCGCATAC, what is the template DNA strand that would be used for transcription?


A) 5-AUGUCGCAUAC-3
B) 5-UACAGCGUAUG-3
C) 3-UACAGCGUAUG-5
D) 3-TACAGCGTATG-5
E) 5-TACAGCGTATG-3

F) A) and B)
G) None of the above

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Order the four steps shown as they would occur, from beginning to end, during expression of a eukaryotic gene. (1) Pre-mRNA is processed to make mRNA. (2) Ribosomes translate the mRNA message to make proteins. (3) mRNA is transported to the cytoplasm. (4) DNA is used as a template to make pre-mRNA.


A) 1, 4, 3, 2
B) 4, 3, 1, 2
C) 4, 1, 3, 2
D) 4, 1, 2, 3
E) 1, 2, 4, 3

F) C) and E)
G) B) and C)

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Which statement about codons and anticodons is true?


A) The codon bonds covalently with the anticodon.
B) They have the same base sequences.
C) There are 64 codons and 61 anticodons.
D) Activating enzymes link codons and anticodons.
E) At contact, the codon and the anticodon are antiparallel to each other.

F) B) and E)
G) A) and C)

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In bacteria, proteins called _______ factors assist transcription by directing the polymerase onto the promoter.

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mRNA is synthesized in the _______ direction, which corresponds to the _______ of the protein.


A) 5ʹ-to-3ʹ; N terminus to C terminus
B) 3ʹ-to-5ʹ; C terminus to N terminus
C) 5ʹ-to-3ʹ; C terminus to N terminus
D) 3ʹ-to-5ʹ; N terminus to C terminus
E) Examples of all of the above have been found.

F) B) and D)
G) C) and D)

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What are the first five amino acids that would be translated from the following mRNA molecule? 5ʹ-...ACGAUACGUAUGCUCGAGAUCCGAGACUAUGUU...-3ʹ

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Methionine (from AUG...

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If codons were read two bases at a time instead of three bases at a time, how many different possible amino acids could be specified?


A) 16
B) 64
C) 8
D) 32
E) 128

F) A) and C)
G) B) and D)

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Refer to the figure. Refer to the figure.   What is the location of the amino acid attachment site of this tRNA molecule? What is the location of the amino acid attachment site of this tRNA molecule?

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In a nucleic acid hybridization experiment performed to detect exons, an appropriate probe would be


A) single-stranded DNA.
B) double-stranded DNA.
C) triple-stranded DNA.
D) single-stranded RNA.
E) double-stranded RNA.

F) C) and D)
G) A) and E)

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If the following synthetic RNA were added to a test tube containing all the components necessary for protein translation to occur, what would the amino acid sequence be? 5-AUAUAUAUAUAU-3


A) Polyphenylalanine
B) Isoleucine-tyrosine-isoleucine-tyrosine
C) Isoleucine-isoleucine-isoleucine-isoleucine
D) Tyrosine-tyrosine-tyrosine-tyrosine
E) Asparagine-asparagine-asparagine-asparagine

F) A) and D)
G) A) and E)

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Suppose the DNA of a gene contains seven regions, A through G, in that order.Regions A, B, E, and G are located in exons, while regions C, D, and F are located in introns.What is the order of the regions in the mature mRNA transcribed from that sequence?


A) AB
B) ABEG
C) ABEGCDF
D) CDF
E) ABCDEFG

F) A) and C)
G) A) and B)

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Transcription is the process of


A) synthesizing a DNA molecule from an RNA template.
B) assembling ribonucleoside triphosphates into an RNA molecule without a template.
C) synthesizing an RNA molecule using a DNA template.
D) synthesizing a protein using information from a messenger RNA.
E) replicating a single-stranded DNA molecule.

F) All of the above
G) B) and D)

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What would happen if a mutation occurred in DNA such that the second codon of the resulting mRNA was changed from UGG to UAG?


A) Translation would continue and the second amino acid would be the same.
B) Nothing; the ribosome would skip that codon, and translation would continue.
C) Translation would continue, but the reading frame of the ribosome would be shifted.
D) Translation would stop at the second codon, and no functional protein would be made.
E) Translation would continue, but the second amino acid in the protein would be different.

F) A) and E)
G) B) and C)

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Exons


A) are translated.
B) are found in most prokaryotic genes.
C) are removed during RNA processing.
D) provide RNA stability.
E) are added after transcription.

F) A) and C)
G) None of the above

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If there were five kinds of nucleotides, a genetic code (with codons that are three nucleotides long) would have _______ different types of codons.

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Inclusion-cell (I-cell) disease is a failure of


A) proteolysis.
B) glycosylation.
C) phosphorylation.
D) the fidelity function.
E) translation.

F) All of the above
G) A) and B)

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