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Which of the following is not an event of phagocytosis?


A) Ingestion
B) Destruction
C) Diapedesis
D) Chemotaxis
E) Phagolysosome formation

F) C) and D)
G) B) and C)

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All of the following are events of early inflammation except


A) macrophages appear first and begin phagocytosis.
B) chemical mediators and cytokines are released.
C) brief vasoconstriction is followed by vasodilation.
D) exudate and pus can accumulate.
E) capillaries become more permeable, resulting in edema.

F) A) and B)
G) B) and D)

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B lymphocytes and T lymphocytes mature in the thymus gland.

A) True
B) False

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All of the following comprise the second line of defense except ______.


A) phagocytosis
B) fever
C) inflammation
D) antibody production
E) complement proteins

F) None of the above
G) A) and C)

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All of the following pertain to platelets,except


A) they are not whole cells but are pieces of cells.
B) they originate from giant multinucleate cells called megakaryocytes.
C) they function in blood clotting and inflammation.
D) they function primarily in hemostasis.
E) they contain hemoglobin to transport oxygen and carbon dioxide.

F) B) and E)
G) None of the above

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Keratin is an important aspect of nonspecific defense because it


A) is toxic to pathogens.
B) destroys pathogens.
C) physically restricts pathogens to a specific region.
D) creates a physical barrier against pathogens.

E) B) and D)
F) B) and C)

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The mononuclear phagocyte system (MPS) is an intricate network throughout the body that comprises


A) connective tissue and monocytes.
B) connective tissue and lymphocytes.
C) connective tissue fibers and phagocytic white blood cells.
D) connective tissue fibers, mast cells, and basophils.

E) B) and C)
F) None of the above

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The second line of defense includes inflammation,phagocytosis,fever,and antimicrobial proteins.

A) True
B) False

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Your 81-year old grandfather has been diagnosed with cancer of the thymus.The doctor is urging surgical removal of the cancer,but you and the family are worried about the consequences of removing an entire organ such as the thymus.Which statement is correct?


A) Your grandfather would not be able to produce complement proteins necessary for pathogen control and inflammation.
B) Your grandfather will have a loss of T lymphocytes and will have an immune deficiency.
C) Your grandfather would not have sufficient phagocytic cells and would not be able to contain bacterial infections.
D) There is nothing to worry about; thymus removal will not affect your grandfather's immune status at his age.

E) A) and B)
F) B) and C)

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The circulating substances that affect the hypothalamus and initiate fever are ______.


A) interferons
B) lysozymes
C) complement
D) leukotrines
E) pyrogens

F) B) and D)
G) B) and C)

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Which of the following is mismatched in relation to inflammation?


A) Tumor - cancer
B) Rubor - redness
C) Dolor - pain
D) Calor - warmth

E) A) and B)
F) All of the above

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You have severe itching problems when bitten by an insect.Your friend gives you an ointment to spread on your skin around the bite so that the redness and itching do not bother you.The likely mechanism of this medication would be


A) the inactivation of neutrophils.
B) the destruction of phagocytic cells.
C) to act as an antagonist of histamine.
D) the inhibition of lysozyme.

E) A) and B)
F) B) and D)

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You cut your finger dicing chicken for dinner.Which of the following is not a source of chemicals that stimulate the inflammatory response that results from the injury?


A) Bacterial cells that infect the wound
B) Antibody-producing plasma cells
C) Localized leukocytes
D) Host tissues damaged by the knife

E) None of the above
F) B) and C)

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Monocytes are the mature form of macrophages; they are found in tissues.

A) True
B) False

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The granules of eosinophils contain ______.


A) peroxidase
B) antigens
C) histamine
D) antibodies
E) serotonin

F) All of the above
G) B) and C)

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Which of the following represents the correct order of activity in the complement cascade?


A) Amplification, initiation, membrane attack, and polymerization
B) Polymerization, initiation, membrane attack, and amplification
C) Initiation, membrane attack, polymerization, and amplification
D) Membrane attack, initiation, polymerization, and amplification
E) Initiation, amplification, polymerization, and membrane attack

F) A) and D)
G) D) and E)

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What is the first step in the major events of the inflammatory process?


A) Activation of complement
B) Vascular reactions
C) Injury and mast cells releasing chemical mediators
D) Formation of pus and edema
E) Scar formation and/or resolution

F) C) and D)
G) A) and B)

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Which of the following fluid compartments is not a partner in immune function?


A) Extracellular fluid
B) Intracellular fluid
C) Blood stream
D) Lymphatic system

E) A) and B)
F) A) and C)

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Which protein can be produced by a virus-infected cell,in order to communicate with other cells that need to produce antiviral proteins?


A) Albumin
B) Histamine
C) Interferon
D) Complement
E) Lysozyme

F) A) and E)
G) C) and E)

Correct Answer

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The chemical found in tears and saliva that hydrolyzes the peptidoglycan in certain bacterial cell walls is ______.


A) lactic acid
B) bile
C) histamine
D) hydrochloric acid
E) lysozyme

F) B) and D)
G) B) and C)

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