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Mycobacterium tuberculosis has chemicals in its cell wall that inhibit the fusion of phagocytic vacuoles with lysosomes.Which statement is true?


A) Complement proteins will take over to destroy the bacteria.
B) Antibodies produced by the cells can more effectively kill the bacteria.
C) The bacterium can survive and replicate inside of the phagocytic cell.
D) The bacterium can produce chemicals which can destroy the macrophage housing the bacterium.

E) None of the above
F) A) and B)

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B lymphocytes and T lymphocytes mature in the thymus gland.

A) True
B) False

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Plasma is also called lymph.

A) True
B) False

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Which body region is protected by fatty acids, acidic pH, lactic acid, and a tough cell barrier with its own normal biota?


A) Eyes
B) Skin
C) Urinary tract
D) Digestive tract
E) Respiratory tract

F) A) and B)
G) A) and C)

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Plasma cells


A) are derived from T lymphocytes.
B) function in cell-mediated immunity.
C) function in blood clotting.
D) produce and secrete antibodies.

E) None of the above
F) A) and B)

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All of the following pertain to platelets, except


A) they are not whole cells but are pieces of cells.
B) they originate from giant multinucleate cells called megakaryocytes.
C) they function in blood clotting and inflammation.
D) they function primarily in hemostasis.
E) they contain hemoglobin to transport oxygen and carbon dioxide.

F) A) and D)
G) A) and C)

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All of the following are physical barriers to pathogens, except ______.


A) hairs
B) T cells
C) unbroken skin
D) mucous
E) tears

F) C) and E)
G) B) and D)

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What is the first step in the major events of the inflammatory process?


A) Activation of complement
B) Vascular reactions
C) Injury and mast cells releasing chemical mediators
D) Formation of pus and edema
E) Scar formation and/or resolution

F) C) and E)
G) All of the above

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Despite not being a physical barrier, the resident microbiota are considered part of the first line of defense since they stimulate inflammation and fever, enhancing pathogen removal.

A) True
B) False

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Certain complement components stimulate inflammation and phagocytosis.

A) True
B) False

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A person will typically experience the sensation of _____ when fever is starting to occur in the body.


A) pain
B) chills
C) sweating
D) heat

E) B) and D)
F) None of the above

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During what process are hypochlorite and hydrogen peroxide produced in order to destroy bacteria and inhibit viral replication?


A) Complement production
B) Inflammation
C) Interferon production
D) Lysozyme production
E) Phagocytosis

F) B) and C)
G) All of the above

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Immune system cells differentiate between self and foreign cells by their ______.


A) markers
B) sizes
C) cell processes
D) shapes
E) cell walls

F) B) and C)
G) A) and E)

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Hematopoiesis is the


A) production of only red blood cells.
B) loss of blood due to hemorrhaging.
C) migration of white blood cells from the blood out to the tissues.
D) production of white blood cells, red blood cells, and platelets.
E) plugging of broken vessels to stop bleeding.

F) A) and B)
G) A) and C)

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Your 81-year old grandfather has been diagnosed with cancer of the thymus.The doctor is urging surgical removal of the cancer, but you and the family are worried about the consequences of removing an entire organ such as the thymus.Which statement is correct?


A) Your grandfather would not be able to produce complement proteins necessary for pathogen control and inflammation.
B) Your grandfather will have a loss of T lymphocytes and will have an immune deficiency.
C) Your grandfather would not have sufficient phagocytic cells and would not be able to contain bacterial infections.
D) There is nothing to worry about; thymus removal will not affect your grandfather's immune status at his age.

E) All of the above
F) None of the above

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The least numerous of all white blood cells that release histamine during inflammation and allergic reactions are ______.


A) eosinophils
B) lymphocytes
C) neutrophils
D) monocytes
E) basophils

F) B) and D)
G) A) and B)

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What structures are found along lymphatic vessels and are heavily clustered in the armpit, groin, and neck?


A) Spleen
B) Thymus
C) GALT
D) Tonsils
E) Lymph nodes

F) A) and B)
G) A) and C)

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The main function of the mononuclear phagocyte system is to provide


A) surveillance cells.
B) a connection between tissues and organs.
C) filtration of extracellular fluid.
D) filtration of blood.

E) A) and D)
F) B) and D)

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One of the major differences between the first and second line of defense is that


A) the first line defenses involve complement proteins whereas the second line defenses involve antibodies.
B) the first line defenses involve the respiratory tract whereas the second line defenses involve the gastrointestinal tract.
C) the first line defenses are mechanisms whereas the second line defenses are physical barriers to infection.
D) the first line defenses are anatomical barriers whereas the second line defenses are mechanisms.

E) A) and B)
F) A) and C)

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The second line of defense includes inflammation, phagocytosis, fever, and antimicrobial proteins.

A) True
B) False

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